I want to strike directly at the heart of what I call The Carb Scam. This Scam has held humans captive throughout the last 10,000 years, and it’s only now that a few people are gathering up the courage to lead a revolution to unseat it, and the low-carb diet is the chief weapon.
It must be clearly understood that enzymes control the flow of fuel within cells and within tissues. In the transition from the fed to the fasted state, the liver switches (in a brief period of several hours) from an organ that uses carbohydrates for fuel and also for fat manufacture, to an organ that uses fat as fuel and produces ketone bodies. These adaptations are directed primarily by an enzyme, Malonyl-CoA (MCoA), with additional control provided by a fat compound and a chemical, carnitine. These enzmatic changes are caused by hormones, particularly the two pancreatic hormones, insulin and glucagon.
What, precisely, does a low-carbohydrate diet do to help us control our weight and to avoid glycation? The three primary aspects of the low-carbohydrate diet include: 1) a means of stimulating our fat stores to release fat, 2) the ability to burn the released fat, and 3) a means of preventing the conversion of carbohydrate into body fat. The scientific terms for these three processes are: 1) lipolysis, 2) oxidation, and 3) lipogenesis. The outcome, however, of this cellular response is the reduction in food intake at the whole body level.
Let’s now review the specifics as to how different foods stimulate their own disposal. First, it must be understood that the fuels themselves are the primary determinants of their own disposal, a response called “humoral.” Foods do this by regulating the activities of enzymes: they control their concentration; they affect other chemicals that adjust the enzyme’s rate of activity; they determine rates of gene expression, the expression of which is responsible for manufacturing the enzymes. Food leads to a release of hormones that are specific to the food eaten. It’s both the amount and the ratio of these hormones that dictate responses at the cellular level. Hormones attach themselves to cell membranes and stimulate changes within the cell, changes that affect enzymes and the genes that manufacture them.